MapDisto


MapDisto splash


MapDisto is a program for mapping genetic markers and quantitative trait loci (QTL) in experimental segregating populations.

NEW: MapDisto 2.1 is now available for the Windows and macOS systems.
Check our
Download page.

There is a Google discussion group about MapDisto here.

Description: MapDisto is very easy to use. It has many features such as finding linkage groups, drawing genetic maps, computing allelic desequilibrium (segregation distortion), automatic ordering of loci, QTL analysis, exporting data and maps for other mapping software, etc... One of its specificities is to propose recombination fraction estimates in case of segregation distortion.
Supported population types are backcross, F2, doubled haploids, RIL-SSD (recombinant lines by single-seed descent), and HRIL (highly recombinant lines).
Have a look at its
features for a complete overview. See also MapDisto links at IBP and mybiosoftware.
MapDisto has been used in many genetic studies. See a
list of publications referring to it.

If you want to cite MapDisto v 2.x in your work, please use this reference:
Heffelfinger, Fragoso and Lorieux (2017) Constructing linkage maps in the genomics era with MapDisto 2.0. DOI: https://doi.org/10.1093/bioinformatics/btx177
If you want to cite MapDisto v 1.x in your work, please use this reference:
Lorieux M (2012) MapDisto: fast and efficient computation of genetic linkage maps. Molecular Breeding 30:1231-1235. DOI 10.1007/s11032-012-9706-y


New features in MapDisto 2.x include:

* handling of very big genotyping datasets like the ones generated by genotyping-by-sequencing (GBS), through a Java plugin by Christopher Heffelfinger
* direct importation of Variant Call Format (VCF) files
* construction of linkage groups in case of segregation distortion
* data imputation on VCF files using a combination of LB-Impute (Fragoso et al, Genetics 2015) and BP-Impute (Fragoso et al 2017, in prep)
* QTL search via new R/qtl interface
* meta-QTL analysis in multiple populations sharing a common parent
* Local recombination analysis

Note: MapDisto needs Microsoft® Excel 2007 or later



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